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Music Boosts Memory in Alzheimer’s Patients

While the parts of the brain where we make memories are the first parts to be ravaged as Alzheimer’s develops, music pulls from other areas, which aren’t as damaged by the disease.

Music’s power to soothe or energize is well known, and there is good science behind the use of music to arouse dormant memories even in those whose minds are failing. Now the results of a recent BU study suggest that music may also help people with dementia retain new information, a finding with promising implications for Americans living with Alzheimer’s.
According to researcher Brandon Ally, a School of Medicine assistant professor of neurology, Alzheimer’s patients who were put through a series of memory tests learned more lyrics when they were set to music rather than just spoken, while healthy elderly people remembered just as much and just as well with or without music.

While the study was small — only 32 subjects — the results, described by Ally as stunning, could lead to a new way of helping Alzheimer’s patients remember things required for their well-being and maintaining their independence. For example, a simple ditty might help patients remember which medications to take when, says Ally, whose research focuses mainly on how memory deteriorates in healthy aging as well as in elderly people with dementia.

In the study, the BU team had a group of healthy elderly people and a group with Alzheimer’s view a series of simple song lyrics on a computer screen, first with the words being sung by a young woman, then with the words being spoken by the same woman, and finally with no accompanying sound at all.

To make sure subjects would have no knowledge of the songs beforehand, Ally and Simmons-Stern, now used only children’s songs written in the last few years and did a random screening to be fairly certain the songs were outside elderly people’s frames of reference.

After seeing and hearing four-line selections from the 80 test lyrics, the subjects were asked if they recognized the lyrics. For those with Alzheimer’s, hearing the song sung significantly improved their recall; for people in the control group, the effect of hearing lyrics spoken or sung or merely appearing as text yielded the same result.

“A lot of groups have looked at how music unlocks past memories — a therapist may play music from the big band era to uncloud an octogenarian’s memories of the war,” says Ally. “But we were the first to show that Alzheimer’s patients can actually learn new information using music.” There have been studies of musicians with dementia who remembered tunes and how to play, but little else. These are what researchers call “procedural” memories, he says, like riding a bike.

Whatever the mechanism, the therapeutic value of music is accepted by the medical establishment, and some forms of music therapy are covered by health insurance.

Ally hopes to repeat the study with a larger sample size, and further investigate why music seemed to have no effect on recognition of test information by healthy adults.

 “I wasn’t expecting to find such a huge benefit to music and learning, and this is something people can use,” says Ally. There’s usually a long lag between study results and practical applications, but in this case “it was like a no-brainer,” he says. “People could use this technique tomorrow.”

We have always encouraged our caregivers to use music during their care of clients with Alzheimer’s.  There is often a magical effect of music and song among folks living with Alzheimer’s at any stage of the disease.  It can calm agitation, relax them and improve their mood.  It even helps with sun downing behaviors.  We now have the scientific studies to confirm their very positive effects of enjoying music and song with our clients’ friends and family members. 

Let’s all fill up those ipads and ipods and start playing and singing along! Thanks to Brandon Ally of Vanderbilt Memory Disorders Research Lab This information was originally released from the Boston University School of Medicine -- BU Today.